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You are here:Home » Antibodies » Abs to Keratin, Cytokeratin » Anti -Keratin 6

Anti -Keratin 6

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Highly Purified E
Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes , which express CK6 and CK16. CK16 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation.
Catalog #K0199-06
ApplicationsSuitable for use in ELISA. Other applications have not been tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No0.N.347
HostMouse
SourceHuman
Concentration~0.2mg/ml
FormSupplied as a liquid in 10mM PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide. Also available without BSA and azide. See K0199-06X.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide (GSSTI-KYTTTS) corresponding to the C-terminus of human keratin 6. Cellular Localization: Cytoplasmic.
SpecificityRecognizes human Keratin 6 at 56kD. Species crossreactivity: mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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