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You are here:Home » Antibodies » Abs to Keratin, Cytokeratin » Anti -KRT14, ID (Keratin, Type I Cytoskeletal 14, Cytokeratin-14, CK-14, Keratin-14, K14)

Anti -KRT14, ID (Keratin, Type I Cytoskeletal 14, Cytokeratin-14, CK-14, Keratin-14, K14)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Keratin 14 is a member of the keratin family, the most diverse group of intermediate filaments. This protein, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. Keratin 14 expresses in most cells of squamous cell carcinomas, in spinous and suprabasal cells around the branching papillary region of papillomas, and weakly in a few proliferative cells of hyperplastic tissue.
Catalog #K0199-17K
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-2ug/ml
Immunohistochemistry: 1.3ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH7.4, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the internal sequence of human keratin 14.
SpecificityRecognizes human keratin 14. Species Crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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