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You are here:Home » Antibodies » Abs to Keratin, Cytokeratin » Anti -KRT17 (Keratin, Type I Cytoskeletal 17, 39.1, Cytokeratin-17, CK-17, Keratin-17, K17)

Anti -KRT17 (Keratin, Type I Cytoskeletal 17, 39.1, Cytokeratin-17, CK-17, Keratin-17,
K17)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified IH
The type I keratin 17 (K17) shows a peculiar localization in human epithelial appendages including hair follicles, which undergo a growth cycle throughout adult life. Additionally K17 is induced, along with K6 and K16, early after acute injury to human skin. Predominant expression of K17 and the frequent expression of K8 and K19, with little K6/K16 and K1/K10 expression are the characteristic features of basal cell carcinomas (BCC). This expresssion indicates BCC is differentiated towards undifferentiated follicular epithelia, most probably hair bulge cells.
Catalog #K0199-20E
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 1:25-1:100
Immunohistochemistry (Frozen): 1:100-1:200
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 20mM Tris-HCl, pH 8.0, 20mg/ml BSA, 0.05% sodium azide.
PurityPurified
ImmunogenSynthetic peptide corresponding to human Cytokeratin 17 conjugated to KLH.
SpecificityRecognizes human KRT17.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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