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You are here:Home » Antibodies » Abs to RNA Processing » Anti -KHSRP, NT (KH Type-splicing Regulatory Protein, KSRP, Far Upstream Element-binding Protein 2, FUSE-binding Protein 2, FBP2, FUBP2, MGC99676, p75) (Biotin)

Anti -KHSRP, NT (KH Type-splicing Regulatory Protein, KSRP, Far Upstream Element-binding
Protein 2, FUSE-binding Protein 2, FBP2, FUBP2, MGC99676, p75) (Biotin)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
KHSRP binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity). It is a part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. It may interact with single-stranded DNA from the far-upstream element (FUSE) and activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
Catalog #K1600-75-Biotin
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-1:500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to Biotin.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide selected from the N-terminal region of human KHSRP (KLH).
SpecificityRecognizes human KHSRP.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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