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Anti -Ki-67 (Antigen Identified by Monoclonal Antibody Ki-67, KIA, MKI67, Proliferation Related Ki-67 Antigen)
Anti -Ki-67 (Antigen Identified by Monoclonal Antibody Ki-67, KIA, MKI67, Proliferation Related Ki-67 Antigen)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
IH IC FC IF |
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| Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms. In neoplastic tissues the prognostic value is comparable to the tritiated thymidine-labelling index. The correlation between low Ki67 index and histologically low-grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation. | | | Catalog # | K1700-11A | | Applications | Suitable for use in Immunofluorescence, Immunocytochemistry, Immunohistochemistry and Flow Cytometry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (Paraffin): 1:100 | | Flow cytometry: 1:100 | | Optimal dilution determined by the researcher. | | Positive Controls | Mouse intestine, pancreas, spleen | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | N/A | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Mouse | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in Tris-citrate/phosphate, pH 7.5, 0.1% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide cooresponding to an internal portion (within residues 1600-1700) of mouse Ki-67 protein. Cellular Localization: Nuclear. | | Specificity | Recognizes mouse Ki-67. Species crossreactivity: human | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | anti-Antigen identified by monoclonal Ki 67 antibody, anti-Antigen KI-67 antibody, anti-KIA antibody, anti-Proliferation related Ki 67 antigen antibody, anti-ki-67 antibody |
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