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You are here:Home » Antibodies » Abs to Motor Proteins » Anti -KIF3A (Microtubule plus end-directed kinesin motor 3A, Kinesin-like protein KIF3A)

Anti -KIF3A (Microtubule plus end-directed kinesin motor 3A, Kinesin-like protein KIF3A)

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IP
KIF3A, a member of the kinesin-like protein family, is a microtubule-based anterograde translocator for membranous organelles (1). The KIF3A motor comprises a heterodimer of the motor proteins KIF3A and KIF3B and an associated protein, KAP3, which binds to the tail ends of KIF3A and KIF3B (2). This heterodimer possesses a plus-end-directed microtubule sliding activity that uses energy derived from ATP hydrolysis. On the other hand, KAP3 links KIF3A/3B with various cargo proteins, including fodrin and the tumor suppressor adenomatous polyposis coli (APC). By binding to fodrin, the KIF3A/3B heterotrimer transports fodrin-associating vesicles that are important for neurite building (3).
Catalog #K1759-17
ApplicationsSuitable for use in Western Blot and Immunoprecipitation. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1:1000-1:10,000
Immunoprecipitation: 1:10-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
Clone NoEPR5087
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH 7.2, 0.05% BSA, 0.01% sodium azide, 50% glycerol.
PuritySupernatant
ImmunogenSynthetic peptide corresponding to residues in human KIF3A.
SpecificityRecognizes human KIF3A. Species crossreactivity: Mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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