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You are here:Home » Antibodies » Abs to GTPase, Rab, Ras, Rho Proteins » Anti -Kinase Suppressor of Ras (KSR, KSR1, BKSR1, dKsr, EK31, hb, Positive Ras Signaling Mediator Family Member, RSU2, Suppressor of Activated let 60 Ras SUR3, Suppressor of Ras1 31, SR31)

Anti -Kinase Suppressor of Ras (KSR, KSR1, BKSR1, dKsr, EK31, hb, Positive Ras Signaling
Mediator Family Member, RSU2, Suppressor of Activated let 60 Ras SUR3, Suppressor of Ras1
31, SR31)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified B IH
KSR was initially considered to be a protein kinase acting in the Ras pathway, but has more recently been demonstrated to act as a scaffold protein, facilitating complex formation between RAF and MEK and ERK.
Catalog #K1775
ApplicationsSuitable for use in Western Blot and Immunohistochemistry
Other applications have not been tested.
Recommended Dilutions
Immunohistochemistry (Frozen and paraffin): Methacarn fixation recommended for paraffin embedded tissues.
Optimal dilutions to be determined by the researcher.
Recommended Secondary ReagentsI1904-49U IgG, F(abí)2, H&L X-Adsorbed (FITC) RbxRt
I1904-49H IgG, F(abí)2, H&L X-Adsorbed (HRP) RbxRt
I1904-47J IgG, H&L (AP) Pab GtxRt
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol 40-50%, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No3H2582
HostRat
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant human KSR protein.
SpecificityRecognizes human kinase suppressor of Ras (KSR). Species Crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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