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You are here:Home » Antibodies » Abs to Extracellular Matrix Proteins » Anti -Kindlin-2 (Fermitin family homolog 2, KIND2, Kindlin-2, MIG2, mig-2, MIG-2, Mitogen-inducible gene 2 protein, PH domain-containing family C member 1, Pleckstrin homology domain-containing family C member 1, PLEKHC1, UNC112, UNC112B, FERMT2)

Anti -Kindlin-2 (Fermitin family homolog 2, KIND2, Kindlin-2, MIG2, mig-2, MIG-2,
Mitogen-inducible gene 2 protein, PH domain-containing family C member 1, Pleckstrin
homology domain-containing family C member 1, PLEKHC1, UNC112, UNC112B, FERMT2)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified B IC
The Kindlin family is a group of focal adhesion proteins that have become a point of interest because of their ability to bind and activate integrins. Abnormalities in this ability have linked Kindlin to several diseases, both inherited and acquired, such as Kindler syndrome, cancer, and leukocyte adhesion deficiency. The isoform Kindlin-2 specifically participates in the recruitment of migfilin protein to focal adhesion sites for cell-ECM interactions, coordinates the manufacture of actin and modifications to cell shape. It is also actively involved in connecting ECM adhesion sites and the actin cytoskeleton (Shi, 2007). Kindlin-2 is pervasively expressed throughout tissue.
Catalog #K1778
Applications
Suitable for use in Western Blot and Immunocytochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.5ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHeLa cell lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1k
Clone No10H13
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.1M Tris-Glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
PurityPurified by ammonium sulfate precipitation.
ImmunogenRecombinant protein corresponding to human Kindlin-2 (GST-tagged).
SpecificityRecognizes human Kindlin-2. Species sequence homology: mouse, rat, bovine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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