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Abs to Transcription Factors, Zinc (Ring) Finger
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Anti -KLF4 (Krueppel-like Factor 4, Epithelial Zinc Finger Protein EZF, Gut-enriched Krueppel-like Factor, EZF, GKLF)
Anti -KLF4 (Krueppel-like Factor 4, Epithelial Zinc Finger Protein EZF, Gut-enriched
Krueppel-like Factor, EZF, GKLF)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
|
| KLF4 is a protein belonging to the krueppel C2H2-type zinc-finger protein family, consisting of three C2H2-type zinc fingers. It functions as a cell cycle checkpoint protein, induces squamous epithelial dysplasia and maintains the integrity of the G2/M checkpoint following DNA damage. KLF4 prevents centrosome amplification following gamma radiation-induced DNA damage and plays a role in the differentiation of epithelial cells and in the development of the skeleton and kidney. Its inactivation leads to bladder carcinogenesis and gastric carcinogenesis. | | | Catalog # | K1891-41C | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 1-3ug/ml | | Immunohistochemistry (paraffin): 10ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Synthetic peptide corresponding to aa1-50 of human KLF4. | | Specificity | Recognizes human KLF4. Species Crossreactivity: bovine, monkey, mouse, rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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