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Abs to Transcription Factors, Zinc (Ring) Finger
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Anti -KLF4 (Krueppel-like Factor 4, Epithelial Zinc Finger Protein EZF, Gut-enriched Krueppel-like Factor, EZF, GKLF)
Anti -KLF4 (Krueppel-like Factor 4, Epithelial Zinc Finger Protein EZF, Gut-enriched
Krueppel-like Factor, EZF, GKLF)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B |
|
| KLF4 is a protein belonging to the krueppel C2H2-type zinc-finger protein family, consisting of three C2H2-type zinc fingers. It functions as a cell cycle checkpoint protein, induces squamous epithelial dysplasia and maintains the integrity of the G2/M checkpoint following DNA damage. KLF4 prevents centrosome amplification following gamma radiation-induced DNA damage and plays a role in the differentiation of epithelial cells and in the development of the skeleton and kidney. Its inactivation leads to bladder carcinogenesis and gastric carcinogenesis. | | | Catalog # | K1891-41H | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 1:64,000 | | Western Blot: 0.1-0.3ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to AVSDALLPSFST-C, from human KLF4, at N-terminal (NP_004226.2). | | Specificity | Recognizes human KLF4. Species sequence homology: Bovine, mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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