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You are here:Home » Antibodies » Abs to Cell Markers » Anti -KLRK1 (Killer Cell Lectin-like Receptor Subfamily K Member 1, CD314, HGNC:18788, D12S2489E, NK Cell Receptor D, NK Lectin-like Receptor, NKLLR, NKG2D Activating NK Receptor, NKG2D Type II Integral Membrane Protein, NKR P2)

Anti -KLRK1 (Killer Cell Lectin-like Receptor Subfamily K Member 1, CD314, HGNC:18788,
D12S2489E, NK Cell Receptor D, NK Lectin-like Receptor, NKLLR, NKG2D Activating NK
Receptor, NKG2D Type II Integral Membrane Protein, NKR P2)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. D12S2489E is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. The first non-coding exon at the 5' end of the D12S2489E transcript is included in the 3' end of the KLRC4 transcript.
Catalog #K1893-28C
Positive Control Human Lymph Node and Human Spleen lysates
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in TBS, pH 7.2, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide: C-KVYSKEDQDLLK, representing the internal region of the human protein according to NP_031386.1.
SpecificitySpecies Crossreactivity: Crossreacts with Human. Expected to crossreact with Mouse, Rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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