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You are here:Home » Antibodies » Abs to DNA Replication, Repair » Anti -Ku70 (DNA Replication, Repair and Recombination Factor)

Anti -Ku70 (DNA Replication, Repair and Recombination Factor)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH IC
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80kD. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq]
Catalog #K7965-01
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:200-1:1000 (ECL)
Immunohistochemistry: 1:200-1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS pH 7.2, 40% glycerol. No preservative added.
PurityPurified by affinity chromatography.
ImmunogenSynthetic peptide
SpecificityRecognizes Ku70. Species Crossreactivity: Human and rodent.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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