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You are here:Home » Antibodies » Abs to Serum Proteins » Anti -Lactoferrin (Lactotransferrin Precursor), LTF, lGIG12, HLF2, Lactoferrin, Lactotransferrin, LF, Talalactoferrin)

Anti -Lactoferrin (Lactotransferrin Precursor), LTF, lGIG12, HLF2, Lactoferrin,
Lactotransferrin, LF, Talalactoferrin)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B
This peptide is derived by enzymatic cleavage of lactoferrin which is a member of the transferrin family of metal-binding proteins found in milk and other secretory fluids and also in blood. Cleavage by pepsin of bovine lactoferrin leads to the release of Lactoferricin B (aa17-41). This peptide is highly basic, possessing five Arg (R) and three Lys (K) residues. In addition, a number of Trp (W) and Phe (F) aromatic residues are present. The two Cys (C) residues from lactoferricin B form a disulfide bond, generating an almost completely cyclical peptide. Nevertheless, the disulfide bond is not required for the antimicrobial potency. Several studies have shown that Lactoferricin B has a broad-spectrum activity against various Gram-positive and Gram-negative bacteria. In addition the peptide has been shown to have antifungal, antiviral and antitumour activity and to bind lipopolysaccharides (LPS, endotoxin). Moreover, it is known to stimulate the adaptive immune response and has anti-inflammatory properties. Lactoferricin B belongs to a large group of cationic antimicrobial peptides.
Catalog #L1021-81E
ApplicationsSuitable for use in Western Blot and Immunoassay. Other applications not tested.
Recommended DilutionsWestern Blot: 1:10
Optimal dilution to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No9G207
HostMouse
SourceBovine
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.
PurityPurified
ImmunogenBovine lactoferricin, KLH conjugate
SpecificityRecognizes bovine Lactoferricin B is highly specific for bovine Lactoferricin B. It detects the QWR antigenic determinant specific for bovine Lactoferricin B, it lacks reactivity with bovine lactoferrin C-lobe, human lactoferrin or lactoferricin H. The QWR sequence recognized by the antibody 5F12.1.2 is not present in lactoferrin in human, pig, mouse, goat, rabbit, horse, rat, cockroach and African clawed frog.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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