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You are here:Home » Antibodies » Abs to IgG Lambda » Anti -Lambda Chain (B cells)

Anti -Lambda Chain (B cells)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E FC
Human immunoglobulins are glycoproteins composed of two disulfide-bonded heavy (H) chain subunits, each of which is linked by interchain disulfide bonds to a light (L) chain forming a tetramolecular complex. There are five classes of immunoglobulins, designated IgG, IgA, IgM, IgD and IgE, which are defined by differences in the constant region of H chains. L chains are divided into kappa or lambda classifications based on structural antigenic differences. All classes of immunoglobulins have been found on the cell surface of B lymphocytes where they function as antigen receptors to elicit antigen-dependent proliferation and secretion of antigen specific soluble circulating antibodies.
Catalog #L1169-05B
ApplicationsSuitable for use in Flow Cytometry and ELISA. Other applications not tested.
Recommended Dilution Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No7H194
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in FBS, 50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl, 0.5 mg/ml Gentamicin Sulfate.
PurityPurified by Protein A affinity chromatography.
ImmunogenHuman Ig
SpecificityRecognizes cell surface lambda chain on B cells.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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