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You are here:Home » Antibodies » Abs to Nuclear Proteins » Anti -Lamin (Mixed clones)

Anti -Lamin (Mixed clones)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant B IH IF
Nuclear Lamins, also known as Class V intermediate filaments, are fibrous proteins providing structural function and transcriptional regulation in the cell nucleus. Nuclear lamins interact with membrane-associated proteins to form the nuclear lamina on the interior of the nuclear envelope. They are involved in the breakdown and reformation of the nuclear envelope during mitosis, as well as the positioning of nuclear pores.
Catalog #L1219-90C
Specificity X67 X167 X223 Xenopus laevis LA, LI, LII LA, LII LII, LIII Bovine LA, C LA, B1, B2, C LB1, B2 Mouse ND ND LB2 Rat -- -- + Human LA, C LA, C LB1, B2 Trout LA, LI, LII LA, LII, (LI) LII, LIII Rat kangaroo -- -- LII, LIII
ApplicationsSuitable for use in Immunofluorescence, Western Blot, and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry: Neat
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone NoMixed
HostMouse
ConcentrationNot determined
FormSupplied as a liquid, 0.09% sodium azide.
PuritySupernatant
ImmunogenNuclear pore complex-lamina fraction of Xenopus laevis (XLKE-A6 cells).
SpecificityRecognizes the karyoskeleton, ie the intermediate filament proteins of the nucleus. Reacts with Lamin isotypes of 60-75kD.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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