You are here:Home
»
Antibodies
»
Abs to Extracellular Matrix Proteins
»
Anti -Laminin 1 (LAMA1, LAMA, Laminin A Chain, Laminin alpha 1 Chain)
Anti -Laminin 1 (LAMA1, LAMA, Laminin A Chain, Laminin alpha 1 Chain)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
E IH IC IF |
|
| Laminin is a basic component of basement membranes that mediates a number of biological functions such as cell adhesion, growth, migration and differentiation. It has been shown to bind to cells through membrane receptors. It is a very complex protein composed of three chains that form a cruciform structure with three short arms and one long arm. The molecule has one heavy (A) chain (Mr ~400kD) and two light (B) chains (Mr ~200kD). Furthermore, there are three types of light chains, B1, B2 and s-laminin. All the chains contain globular domains, rod-like domains with cysteine-rich repeats and an azhelical domain that participates in the triple coiled-coil structure forming the long arm of the molecule. Additionally, the A chain has a large C-terminal globule, termed domain G. The gene encoding the laminin protein maps to 18p11.31 region of human chromosome. | | | Catalog # | L1225-33 | | Applications | Suitable for use in ELISA, Immunofluorescence and Immunohistochemistry. Other applications not tested. | | Recommended Dilutions | ELISA: >1:1000 | | Immunofluorescence: Immunocytochemistry | | Immunohistochemistry (Frozen, paraffin): 1:200-1:1000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Concentration | Not Determined | | Form | Supplied as a liquid, 0.1% sodium azide. | | Purity | Serum | | Immunogen | Purified laminin 1 from Engelbreth-Holm-Swarn (EHS). Cellular Localization: Extracellular. Found in the basement membranes. | | Specificity | Recognizes both the A (400kD) and B (220kD) chains of Laminin 1. Species Crossreactivity: human, avian, chicken and rabbit | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
