Anti -Laminin, alpha 2 (Laminin Subunit alpha-2, LAMA2, Laminin M Chain, LAMM, Laminin-2
Subunit alpha, Laminin-4 Subunit alpha, Laminin-12 Subunit alpha, Merosin Heavy Chain)
(Azide Free)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B IH |
|
| Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene. [provided by RefSeq] | | | Catalog # | L1225-47 | | Applications | Suitable for use in ELISA, Immunohistochemistry (paraffin), and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 1ug/ml-3ng/ml | | Western Blot: 1:500-1:1,000 | | Immunohistochemistry (paraffin): 1.5ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 11C364 | | Host | Mouse | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in PBS, pH 7.2. No preservative added (Azide free). | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Recombinant protein corresponding to aa3013-3123 of human Laminin alpha 2 subunit. | | Specificity | Recognizes human Laminin alpha 2 subunit. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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