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You are here:Home » Antibodies » Abs to Extracellular Matrix Proteins » Anti -Laminin, beta 1 (LAMB1, CLM, Laminin Subunit beta-1, Laminin B1 Chain, Laminin-1 Subunit beta, Laminin-2 Subunit beta, Laminin-6 Subunit beta, Laminin-8 Subunit beta, Laminin-10 Subunit beta, Laminin-12 Subunit beta, MGC142015)

Anti -Laminin, beta 1 (LAMB1, CLM, Laminin Subunit beta-1, Laminin B1 Chain, Laminin-1
Subunit beta, Laminin-2 Subunit beta, Laminin-6 Subunit beta, Laminin-8 Subunit beta,
Laminin-10 Subunit beta, Laminin-12 Subunit beta, MGC142015)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites B IH IC
Laminin, a major structural glycoprotein of the basement membranes, is an attachment and survival factor for epithelial cells and can also promote the growth of epithelial cells. Laminin plays an important role in both the structural organization of basement membranes and in the anchorage of cells. The monoclonal antibody, DG10 and BC17 against laminin chain beta1 and gamma1, respectively can be widely applied in immunohistochemical studies as all basement membranes contain laminin trimers containing these chains. Antibodies to laminin chains are useful in basic biology studies as well as in pathological studies concerning, for instance, the integrity of the basement membranes in carcinomas. Clone DG 10 against laminin beta1-chain is apparently one of the few laminin antibodies working perfectly in immunoblotting, thus making it especially valuable for biochemical studies.
Catalog #L1226-12
ApplicationsSuitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications tested.
Recommended DilutionWestern Blot: Reacts under reducing and nonreducing conditions
Immunohistochemistry: Frozen
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone NoDG10
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, 1% BSA, 0.1 % sodium azide.
PuritySerum
ImmunogenPartially pepsin-digested laminins from human placenta
SpecificityRecognizes the Mr 220000 b1-chain of human laminin. Reacts with the NH2-terminus of the Ln b1chain.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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