You are here:Home
»
Antibodies
»
Abs to Extracellular Matrix Proteins
»
Anti -Laminin B2, gamma 1 (LAMC1, Laminin B2 Chain, Laminin Gamma 1 Chain, MGC87297)
Anti -Laminin B2, gamma 1 (LAMC1, Laminin B2 Chain, Laminin Gamma 1 Chain, MGC87297)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
IH |
|
| Laminins are large heterotrimeric, noncollagenous glycoproteins composed of alpha, beta, and gamma chains. They are ubiquitously present in basement membrane (BM) along with entactin/ nidogen (EN), collagen type IV (CIV) and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms. | | | Catalog # | L1227-12 | | Applications | Suitable for use in Immunohistochemistry (paraffin-embedded sections). Other applications not tested. | | Recommended Dilution | Immunohistochemistry: 2-4ug/ml for 30 minutes at RT. For staining of formalin-fixed tissues, digest sections with Protease XXV at 1mg/ml in PBS for 5 minutes at 37°C. | | Optimal dilutions to be determined by the researcher. | | Cellular Localization | Basement membrane. | | Positive Control | LS174T cells. Skin tissue sections. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a,k | | Clone No | 8L560 | | Host | Mouse | | Source | Rat | | Concentration | As reported | | Form | Supplied as a liquid in PBS, pH7.4, containing 0.2% BSA and 0.09% sodium azide. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | Rat glomerular basement membrane. | | Specificity | Recognizes rat Laminin B2, gamma 1. Species Crossreactivity: human and guinea pig | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
