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You are here:Home » Antibodies » Abs to Disease Markers » Anti -Large Proteoglycan (Versican, Chondroitin Sulfate Proteoglycan Core Protein 2, CSPG2, DKFZp686K06110, ERVR, Glial Hyaluronate Binding Protein, GHAP, Large Fibroblast Proteoglycan, PGM, V1 Neo, VCAN, Versican Core Protein, Versican Proteoglycan, Versican V

Anti -Large Proteoglycan (Versican, Chondroitin Sulfate Proteoglycan Core Protein 2,
CSPG2, DKFZp686K06110, ERVR, Glial Hyaluronate Binding Protein, GHAP, Large Fibroblast
Proteoglycan, PGM, V1 Neo, VCAN, Versican Core Protein, Versican Proteoglycan, Versican V

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Versican is a large multi-domain chondroitin sulfate proteoglycan. It is secreted by fibroblasts and other types of cells. It has a N-terminal hyaluronic acid (HA) binding domain. This domain has homology with the G1 and G2 domains of aggrecan (G1 is the hyaluronic acid binding region), to cartilage link protein which stabilizes the binding of aggrecan to hyaluronic acid, and, to the hyaluronate receptor CD44. In addition, Versican also has a lectin-like domain, a C-terminal compliment repeat, and two EGF-like repeats, all of which can be found in aggrecan. Versican has an apparent molecular mass of ~1000kD, of which the core contributes 400kD from the 2409 amino acids, and the 12-15 covalently attached chondroitin sulfate chains make up the rest.
Catalog #L1350-04A
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1ug/ml. Detects a band at ~70kD.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~2mg/ml
FormSupplied as a liquid in PBS, pH 7.6, 1mg/ml BSA, 0.1% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa436-441, CGG-DPEAAE, of human Versican. Cellular Localization: Secreted, extracellular matrix.
SpecificityRecognizes human Versican. Species Sequence Homology: Mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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