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Anti -LAT (Linker for Activation of T Cells, Linker for Activation of T cells Family Member 1, LAT1, 36kD Phospho-tyrosine Adapter Protein, p36,38, pp36)
Anti -LAT (Linker for Activation of T Cells, Linker for Activation of T cells Family
Member 1, LAT1, 36kD Phospho-tyrosine Adapter Protein, p36,38, pp36)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
IH |
|
| Mammalian cells have several amino acid transport systems. These systems have been defined by both activity and specific genes. L-type amino acid transporter 1 (LAT1) is a 12 membrane-spanning protein. LAT1 is a Na + -independent neutral amino acid transporter agency and essential for the transporter of large neutral amino acid such as Leucine, Isoleucine, and Valine through the plasma membrane. LAT1 has been proposed to be one of the major nutrient transport systems at the blood-brain barrier. Drugs such as L Dopa are transported by LAT1. LAT1 is thought to be up-regulated to support the high protein synthesis for cell growth in some tumor cell lines | | | Catalog # | L1390-01H | | Cellular Localization | Integral Membrane Protein | | Positive Control | Human spleen or tonsil. | | Applications | Suitable for use in Immunohistochemistry (paraffin-embedded sections). Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.79mg/ml | | Form | 140mM Sodium chloride, 10mM Potassium phosphate [pH 7] | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | KLH conjugated synthetic peptide RHRKPEL representing a portion of the sequence of Human LAT1. | | Specificity | Species Crossreactivity: Crossreacts with human. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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