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You are here:Home » Antibodies » Abs to T Cells » Anti -LAT (Linker for Activation of T Cells, Linker for Activation of T cells Family Member 1, LAT1, 36kD Phospho-tyrosine Adapter Protein, p36-38, pp36) (PE)

Anti -LAT (Linker for Activation of T Cells, Linker for Activation of T cells Family
Member 1, LAT1, 36kD Phospho-tyrosine Adapter Protein, p36-38, pp36) (PE)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IH
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
Catalog #L1390-05B-PE
ApplicationsSuitable for use in FLISA, Immunohistochemistry (paraffin), and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:500-1:1,000
Immunohistochemistry (paraffin): 1.5ug/ml
FLISA: 1ug/ml-3ng/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months after receipt at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG1
Clone No11C369
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to R-Phycoerythrin (R-PE).
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant protein with a GST tag corresponding to a portion within aa1-234 of human LAT.
SpecificityRecognizes human LAT.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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