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Anti -LATS2 (Large Tumor Suppressor Homolog 2, LATS-2, Kinase Phosphorylated During Mitosis, KPM, Serine/Threonine Protein Kinase kpm, Warts-like Kinase)
Anti -LATS2 (Large Tumor Suppressor Homolog 2, LATS-2, Kinase Phosphorylated During
Mitosis, KPM, Serine/Threonine Protein Kinase kpm, Warts-like Kinase)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP |
|
| This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. | | | Catalog # | L1397-85 | | Applications | Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Tris-citrate/phosphate pH 7-8 | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | The epitope that this antibody recognizes maps to a region between residues 1 and 50 of human Large Tumor Suppressor 2 using the numbering given in entry NP_055387.1. | | Specificity | Recognizes human LATS2. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | LATS 2, LATS-2, Large Tumor Suppressor 2 |
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