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Anti -LATS2 (Large Tumor Suppressor Homolog 2, LATS-2, FLJ13161, Kinase Phosphorylated During Mitosis Protein, KPM, Serine/threonine-protein Kinase LATS2, Serine/threonine-protein Kinase kpm, Warts-like Kinase)
Anti -LATS2 (Large Tumor Suppressor Homolog 2, LATS-2, FLJ13161, Kinase Phosphorylated
During Mitosis Protein, KPM, Serine/threonine-protein Kinase LATS2,
Serine/threonine-protein Kinase kpm, Warts-like Kinase)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B IH |
|
| LATS2 is a serine/threonine protein kinase belonging to the LATS tumor suppressor family. This protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. | | | Catalog # | L1397-85B | | Applications | Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | ELISA: 1:1,000 | | Western Blot: 1:100-1:500 | | Immunohistochemistry: 1:10-1:50 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.25mg/ml | | Form | Supplied as a liquid in PBS, 0.09% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Synthetic peptide selected from the center region of human LATS2 (KLH). | | Specificity | Recognizes human LATS2. Species Crossreactivity: mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | LATS, Large Tumor Suppressor, Homolog 2 (Drosophila), EC=2.7.11.1 |
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