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Anti -Lck (Lymphocyte-specific Tyrosine Kinase)
Anti -Lck (Lymphocyte-specific Tyrosine Kinase)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
B |
|
| Lymphocyte-specific protein-tyrosine kinase (Lck), also known as p56Lck and Lsk, is a member of the Src family of non-receptor tyrosine kinases. First identified as a gene rearranged and overexpressed in murine lymphomas, lck behaves as a proto-oncogene and its activation can lead to cellular transformation. Lck protein is anchored to the plasma membrane and interacts with the intracellular domains of CD4/CD8 co-receptors in T lymphocytes. | | | Catalog # | L1565-02D | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 0.5ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | Not determined | | Form | Supplied as a lyophilized powder from PBS with 5% trehalose. Reconstitute with sterile PBS. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Recombinant corresponding to aa1-66 from human Lck expressed in E. coli (P06239). | | Specificity | Recognizes human Lck. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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