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You are here:Home » Antibodies » Abs to Tyrosine Kinases » Anti -Lck (Lymphocyte-specific Tyrosine Kinase)

Anti -Lck (Lymphocyte-specific Tyrosine Kinase)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified B
Lymphocyte-specific protein-tyrosine kinase (Lck), also known as p56Lck and Lsk, is a member of the Src family of non-receptor tyrosine kinases. First identified as a gene rearranged and overexpressed in murine lymphomas, lck behaves as a proto-oncogene and its activation can lead to cellular transformation. Lck protein is anchored to the plasma membrane and interacts with the intracellular domains of CD4/CD8 co-receptors in T lymphocytes.
Catalog #L1565-02D
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
ConcentrationNot determined
FormSupplied as a lyophilized powder from PBS with 5% trehalose. Reconstitute with sterile PBS.
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant corresponding to aa1-66 from human Lck expressed in E. coli (P06239).
SpecificityRecognizes human Lck.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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