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You are here:Home » Antibodies » Abs to Adapter Proteins » Anti -Lck Interacting Molecule (Lck-interacting Molecule, LIME, LIME1, dJ583P15.4, FLJ20406, Lck Interacting Transmembrane Adaptor 1, Lck-interacting Transmembrane Adapter 1, Lck-interacting Membrane Protein, LP8067, RP4-583P15.5)

Anti -Lck Interacting Molecule (Lck-interacting Molecule, LIME, LIME1, dJ583P15.4,
FLJ20406, Lck Interacting Transmembrane Adaptor 1, Lck-interacting Transmembrane Adapter
1, Lck-interacting Membrane Protein, LP8067, RP4-583P15.5)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified B
Lck Interacting Molecule is a new raft-associated adaptor protein involved in regulation of T cell activation by coreceptors. Lck Interacting Molecule becomes tyrosine phosphorylated after cross-linking of the CD4 or CD8 coreceptors. Phospho-Lck Interacting Molecule associates with the Src family kinase Lck and its negative regulator, Csk. Ectopic expression of Lck Interacting Molecule in Jurkat T cells results in an increase of Csk in lipid rafts, increased phosphorylation of Lck and higher Ca2+ response to CD3 stimulation.
Catalog #L1566-09
ApplicationsSuitable for use in Western Blot. Other applications tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a
Clone NoLIME-10
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 15mM sodium azide.
PurityPurified
ImmunogenCOOH-terminal peptide corresponding to residues 281-296 of the human Lck Interacting Molecule (KLH)
SpecificityRecognizes the human Lck Interacting Molecule.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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