LD78-beta, otherwise known as CCL3L1 is a member of the CC chemokine family closely related to MIP-1 alpha (LD78-alpha/CCL3), which acts as a chemoattractant for lymphocytes and monocytes, and is a potent inhibitor of HIV entry, thorough binding to the HIV co-receptor CCR5.
Applications
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution
ELISA: 0.5-2ug/ml Western Blot: 0.1-0.2ug/ml Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Immunogen
Recombinant human LD78-beta, expressed in E. coli.
Form
Supplied as a lyophilized powder in PBS, pH7.2. Reconstitute with 100ul sterile dH20.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes human LD78-beta.