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You are here:Home » Antibodies » Abs to Lectins » Anti -Lectin, Mannose-binding 1 (LMAN1, Endoplasmic Reticulum-Golgi Intermediate Compartment Protein 53, Intracellular Mannose Specific Lectin)

Anti -Lectin, Mannose-binding 1 (LMAN1, Endoplasmic Reticulum-Golgi Intermediate
Compartment Protein 53, Intracellular Mannose Specific Lectin)

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Specifications

Clone Host Grade Applications
Polyclonal Chicken Affinity Purified B
LMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.
Catalog #L1662-85
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgY
HostChicken
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.02% sodium azide
PurityPurified by immunoaffinity chromatography
ImmunogenRecombinant protein corresponding to aa 270-470 of human LMAN1 (UniProt Accession #P49257)
SpecificityRecognizes human LMAN1
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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