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Anti -Leptin (Ob, Obese Protein, Obesity Factor)
Anti -Leptin (Ob, Obese Protein, Obesity Factor)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Highly Purified |
E B IP |
|
| Leptin inhibits food intake and stimulates energy expenditure. Leptin also has thermogenic actions and regulates enzymes of fatty acid oxidation. Severe hereditary obesity in rodents and humans is caused by defects in leptin production. In addition to its critical role in the physiologic regulation of body weight leptin has a variety of other physiologic and pathologic functions resembling those of cytokines. These functions include the regulation of hematopoiesis, angiogenesis, wound healing, inflammation, and immune responses. | | | Catalog # | L1669-01G | | Applications | Suitable for direct ELISA, Western Blot and Immunoprecipitation. Other applications not tested. | | Recommended Dilution | Direct ELISA: 1:10,000 dilution will yield 0.8 O.D. using alkaline phosphatase conjugated rabbit anti-mouse Ig. | | Optimal dilutions to be determined by researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute by adding sterile 40-50% glycerol. Aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 5C73 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a lyophilized powder in PBS, pH 7.2. | | Reconstitution | Reconstitute with 500ul sterile 40-50% glycerol, dH2O. | | Purity | Purified by ion exchange chromatography. | | Immunogen | Recombinant human leptin. MW: 16kD | | Specificity | Recognizes human Leptin. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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