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Anti -Leptin (Ob, Obese Protein, Obesity Factor) (Biotin)
Anti -Leptin (Ob, Obese Protein, Obesity Factor) (Biotin)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B |
|
| Leptin, a 16KD major adipose-derived hormone and member of the leptin family, which plays a key role in appetite control and the regulation of energy expenditure. | | | Secreted leptin associates with proteins within the bloodstream and is transported to the brain, where it inhibits or up-regulates the activity of neuropeptides such as neuropeptide Y (NPY) and alpha-melanocyte-stimulating hormone respectively. Leptin is a recognised marker of obesity, with a correlation between circulating levels of leptin and body fat mass, and defects in leptin production result in severe obesity. Regulators of leptin expression include insulin, cortisol, cAMP and thiazolidinediones. | | | | | | Applications: | | | Suitable for use in ELISA and Western Blot. Other applications not tested. | | | Catalog # | L1669-03B | | Recommended Dilution | ELISA: 0.25-1ug/ml | | Western Blot: 0.1- 0.2ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute by adding sterile 40-50% glycerol, ddH2O. Aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a lyophilized powder in PBS, pH 7.2.Labeled with Biotin. Reconstitute with 0.5ml sterile 40-50% glycerol, PBS, 0.1% BSA. | | Purity | Purified by affinity chromatography. | | Immunogen | Recombinant human leptin. | | Specificity | Recognizes human leptin, a 16KD major adipose-derived hormone and member of the leptin family, which plays a key role in appetite control and the regulation of energy expenditure. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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