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You are here:Home » Antibodies » Abs to Obesity Proteins » Anti -Leptin (LEP, Leptin Murine Obesity Homolog, Leptin Precursor Obesity Factor, Ob, Obese Protein, Obesity, Obesity Factor, Obesity Homolog Mouse, OBS)

Anti -Leptin (LEP, Leptin Murine Obesity Homolog, Leptin Precursor Obesity Factor, Ob,
Obese Protein, Obesity, Obesity Factor, Obesity Homolog Mouse, OBS)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse E
Leptin, the product of the ob (obese) gene, is a 16kD protein consisting of 146 amino acid residues. Leptin is produced in the adipose tissue, and is considered to play an important role in appetite control, fat metabolism and regulation of body weight. It targets the central nervous system, particularly hypothalamus, affecting food intake. Leptin levels are high in most obese individuals. Studies have shown that it may also influence reproductive function.
Catalog #L1670-12A
Cellular Localization Secreted
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No8L578
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityAs reported
ImmunogenRecombinant full length protein (Human).
SpecificityThis antibody recognizes recombinant human leptin and leptin circulating in human blood. Species Crossreactivity: Crossreacts with Human. Not yet tested in other species, but may crossreact with mouse and rat due to 85% and 84% sequence homology respectively.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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