Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Protein Kinase Substrates » Anti -LSP1, Phosphorylated (Ser252) (Lymphocyte-specific Protein 1, 47kD Actin-binding Protein, 52kD Phosphoprotein, pp52, Lymphocyte-specific Antigen WP34, WP34)

Anti -LSP1, Phosphorylated (Ser252) (Lymphocyte-specific Protein 1, 47kD Actin-binding
Protein, 52kD Phosphoprotein, pp52, Lymphocyte-specific Antigen WP34, WP34)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Leukocyte-specific protein (LSP; also known as Lymphocyte- specific protein, SP34 and pp52) is a 52kD filamentous-actin- binding intracellular phosphoprotein. Human LSP1 is composed of 339aa, which expressed in normal and transformed B- lineage cells and normal T-lymphocytes. Studies show that LSP1 plays an important role in cytoskeletal architecture and motility regulation as well as receptor-induced apoptosis. Research show that LSP1 has at least three and potentially a fourth F-actin binding domain located in the basic C-terminal half. This F-actin binding sites are also correspond to the caldesmon and the villin headpiece proteins. LSP1 246-295 containing sequences homologous to caldesmon F-actin binding site II (CII) can bind F-actin.
Catalog #L2030-01A
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-2ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide (RQA-pS-IEL) corresponding to the C-terminus of human LSP1 at the phosphorylated site of Serine 252.
SpecificityRecognizes human LSP1, when phosphorylated at Serine 252. Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links