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You are here:Home » Antibodies » Abs to Transcription Factors, Zinc (Ring) Finger » Anti -LIMS1 (LIM and Senescent Cell Antigen-like Domains 1, Lims1l, 2310016J22Rik, 4921524A02Rik, AI507642, AU021743, C430041B13Rik, AW551584, Particularly Interesting New Cys-His Protein 1, PINCH, PINCH1, Renal Carcinoma Antigen NY-REN-48)

Anti -LIMS1 (LIM and Senescent Cell Antigen-like Domains 1, Lims1l, 2310016J22Rik,
4921524A02Rik, AI507642, AU021743, C430041B13Rik, AW551584, Particularly Interesting New
Cys-His Protein 1, PINCH, PINCH1, Renal Carcinoma Antigen NY-REN-48)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B FC
LIM and senescent cell antigen-like domains 1 (LIMS1, PINCH1) is an adaptor protein which contains five LIM domains. LIM are two zinc finger motifs with links to regulatory function (1). LIMS1 is thought to be involved in integrin and growth factor signaling. During integrin signaling, LIMS1 interacts with ILK, through its LIM domain. LIMS1 also acts as a bridge linking ILK to NCK2, assisting in growth factor signaling pathways. LIMS1 has been linked to coupling surface receptors to downstream signaling molecules involved in the regulation of cell differentiation, cell proliferation, and cell survival (2).
Catalog #L2207-10
ApplicationsSuitable for use in Western Blot and Flow Cytometry. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-1:5000
Flow Cytometry: 1:20
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
IsotypeIgG
Clone No9H444
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 50mM Tris-Glycine, pH 7.4, 0.15M sodium chloride, 40% Glycerol, 0.01% sodium azide, 0.05% BSA.
PuritySupernatant
ImmunogenA synthetic peptide corresponding to residues within LIM zinc-binding 3 region of human LIMS1.
SpecificityRecognizes human LIMS1. Species Crossreactivity: Mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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