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Anti -Lipocalin 2 (HNL, NGAL, Neutrophil Gelatinase Associated Lipocalin, Oncogene 24p3, Neutrophil gelatinase-associated lipocalin precursor P25, alpha-2 microglobulin-related subunit of MMP-9)
Anti -Lipocalin 2 (HNL, NGAL, Neutrophil Gelatinase Associated Lipocalin, Oncogene 24p3,
Neutrophil gelatinase-associated lipocalin precursor P25, alpha-2 microglobulin-related
subunit of MMP-9)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B |
|
| Neutrophil Gelatinase Associated Lipocalin (NGAL) belongs to a family of lipocans which include 25 proteins (including alpha1-microglobulin and beta-lactoglobulin), which are characterized by their ability to bind small lipophilic substances in their hydrophobic core. They thereby serve as transporters of substances like retinal, biliverdins & prostaglandins. There are indications that NGAL is involved in modulation of the inflammatory response and is found in the plasma of patients after stroke. Human neutrophil gelatinase-associated lipocalin (NGAL), and its mouse analog 24p3, are members of the lipocalin family of small secreted proteins. These proteins are up-regulated in a number of pathological conditions, including cancers, and may function as transporters of essential factors. | | | Catalog # | L2499-17 | | Applications | Suitable for use in ELISA and Western Blot. Not suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilution | ELISA: 1:200 | | Western Blot: 1:50 | | Optimal dilutions to be determined by the researcher. | | Culture Medium | RPMI 1640 with 10% fetal calf serum | | Hybridoma | X63-Ag8.653 myeloma cells with spleen cells from Balb/c mice. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | Clone Type | Monoclonal | | Isotype | IgG1,k | | Clone No | 2C10 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 15mM sodium azide. | | Purity | Purified by Protein A/G affinity chromatography from culture supernatant. | | Immunogen | Human recombinant Lipocalin 2 (NGAL) in monomer and dimer forms adsorbed to aluminum hydroxide gel. | | Specificity | Recognizes human Lipocalin 2. Reacts weakly in unreduced forms of NGAL and not at all with reduced forms of NGAL in western blot of SDS-PAGE gels. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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