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Anti -Lipoprotein Receptor, Low Density (LDLR, LDL Receptor) (Biotin)
Anti -Lipoprotein Receptor, Low Density (LDLR, LDL Receptor) (Biotin)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B IH FC |
|
| The LDL receptor (160kD mature or glycosylated receptor; 120kD precursor or unglycosylated receptor) plays a key role in cellular cholesterol homeostasis. | | | Catalog # | L2601-02A | | Application | Suitable for use in ELISA, Immunohistochemistry, Flow Cytometry, Western Blot and Analysis of LDL receptor function in patients with familial hypercholesterolemia. Other applications have not been tested. | | Recommended Dilution | Immunohistochemistry: 1:10 | | Optimal dilutions to be determined by the researcher. | | Positive Control | HepG2 cells and liver sections | | Negative Control | NIH 3T3 cells and normal skin | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2b,k | | Clone No | 4C5 | | Host | Mouse | | Source | Human | | Concentration | ~0.2mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.5% BSA, before the addition of glycerol to 40%. Labeled with Biotin | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Purified bovine adrenal cortex LDL Receptor | | Specificity | Recognizes an epitope in the region of repeat #1 of the ligand binding region. Species Crossreactivity: human and bovine. Does not recognize rat, mouse, hamster, canine or rabbit. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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