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You are here:Home » Molecular Biology » MB-Lipoproteins » Lipoprotein, Low Density, Oxidized, Human (LDL)

Lipoprotein, Low Density, Oxidized, Human (LDL)

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Specifications

Low density lipoprotein (LDL) oxidative modification is one of the major processes involved in atherosclerosis along with other degenerative disorders. Oxidised LDL is preferentially accumulated by macrophages which become so called "foam cells" within the atheromatous plaque and contributes to the accumulation of cholesterol, typical of atherosclerosis.
Catalog #L2601-10M
ApplicationsSuitable for use in Functional Assays. Other applications not tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C. Do not freeze. Aliquots are stable for 4 weeks. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
SourceHuman plasma
PurityPurified to homogeneity by ultra-centrifugation. Oxidized using 20uM cupric sulfate in PBS at 37ºC for 24 hours. Oxidation is terminated with excess EDTA. The level of oxidation is measured using TBARS (Thiobarbituric acid reactive substances) determination using a Malondialdehyde (MDA) standard.
Concentration~2mg/ml
FormSupplied as a liquid in PBS, 0.3mM EDTA.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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