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You are here:Home » Molecular Biology » MB-Lipoproteins » Lipoprotein, Low Density, Human (LDL)

Lipoprotein, Low Density, Human (LDL)

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LDL constitutes 50% of the total lipoprotein mass in plasma and is the major carrier of cholesterol and cholesteryl esters. LDL levels strongly correlate with coronary heart disease. Cholesterol is an important normal constituent of the body. It is part of the structure of cell membranes, bile acids and steroid hormones. Since cholesterol is water insoluble, most cholesterol is carried in the blood by lipoproteins. Lipoproteins are large protein-like molecules, including chylomicrons, VLDL, LDL and HDL. Chylomicrons are lipoproteins that are present shortly after a meal. They disappear within about 2 hours in "normal" people. The main function of LDL seems to be to carry cholesterol to various tissues throughout the body. LDL is sometimes referred to as "bad" cholesterol because elevated levels of LDL correlate most directly with coronary heart disease.
Catalog #L2601-14
Prepared by sequential flotation ultracentrifugation technique using KBr for density adjustments.
Storage and StabilityMay be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
SourceHuman plasma
Purity95% of total lipoprotein content by electrophoresis. Single arc by IEP against antisera to whole human serum. Essentially free from other plasma lipoproteins as determined by electrophoresis using Fast Red 7B staining for lipids and Coomassie Blue for proteins.
Concentration~7mg/ml
FormSupplied as a sterile-filtered liquid in 150mM sodium chloride, 10mM EDTA, pH 7.4. No preservative added.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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