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You are here:Home » Antibodies » Abs to Adapter Proteins » Anti -LNK (Lymphocyte Adapter Protein, Lymphocyte Specific Adapter Protein Lnk, SH2B Adaptor Protein 3, SH2B3, Signal Transduction Protein Lnk)

Anti -LNK (Lymphocyte Adapter Protein, Lymphocyte Specific Adapter Protein Lnk, SH2B
Adaptor Protein 3, SH2B3, Signal Transduction Protein Lnk)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
T-cell activation requires stimulation of the T-cell receptor (TCR; see MIM 186880)-CD3 (see CD3Z; MIM 186780) complex, followed by recruitment of an array of intracellular signaling proteins (e.g., GRB2 (MIM 108355) and PLCG1 (MIM 172420)). Mediating the interaction between the extracellular receptors and intracellular signaling pathways are adaptor proteins such as LAT (MIM 602354), TRIM (MIM 604962), and LNK.[supplied by OMIM]
Catalog #L3220-50
Positive Control Tcell line MOLT4 lysate
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormTris saline containing 0.02% Na azide [pH7.3] with 0.5% BSA
PurityPurified by immunoaffinity chromatography.
ImmunogenCorresponding to amino acids NGPALQPSSPC, from the N Terminus of the LNK protein sequence according to NP_005466.
SpecificitySpecies Crossreactivity: Crossreacts with Human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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