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You are here:Home » Biochemicals » Biochem-Neurochemicals » a-Lobeline Hydrochloride (L-Lobeline hydrochloride; (-)-Lobeline hydrochloride; (-)-a-Lobeline Hydrochloride; 2-[(2R,6S)-6-[(2S)-2-Hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenylethanone hydrochloride)

a-Lobeline Hydrochloride (L-Lobeline hydrochloride; (-)-Lobeline hydrochloride;
(-)-a-Lobeline Hydrochloride;
2-[(2R,6S)-6-[(2S)-2-Hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenylethanone
hydrochloride)

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Specifications

A neuronal nicotinic acetylcholine receptor agonist. A respiratory stimulant.
Catalog #L3355
SourceSynthetic
Purity~90%
SolubilityWater, Methanol
Melting Point178-180°C
Method for Determining IdentityProton NMR Spectroscopic Analysis
TLC ConditionsSiO2; Dichloromethane: Methanol: NH4OH; 9ml: 1ml:5 drops; Visualized with UV and KMnO4; Single spot; Rf=0.6
Chloride Content9.43%
Optical Rotation (in water)-57.9º (c=0.311)
Storage and StabilityMay be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
CAS Number134-63-4
Molecular FormulaC22H28ClNO2
Molecular Weight373.92
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
Alternate namesL-Lobeline hydrochloride; (-)-Lobeline hydrochloride; (-)-a-Lobeline Hydrochloride; 2-[(2R,6S)-6-[(2S)-2-Hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenylethanone hydrochloride


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