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You are here:Home » Antibodies » Abs to Enzymes, Deacetylase » Anti -LSD1 (Lysine-Specific Histone Demethylase, Amine Oxidase Flavin-containing Domain Protein 2, AOF2, BRAF35 HDAC Complex Protein BHC110, Flavin Containing Amine Oxidase Domain Containing Protein 2, KDM 1, KIAA0601)

Anti -LSD1 (Lysine-Specific Histone Demethylase, Amine Oxidase Flavin-containing Domain
Protein 2, AOF2, BRAF35 HDAC Complex Protein BHC110, Flavin Containing Amine Oxidase
Domain Containing Protein 2, KDM 1, KIAA0601)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH
The amine oxidase domain 2 AOF2 gene encodes a nuclear protein (LSD1,~95kD) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serves as a docking module for the stabilization of the associated corepressor complex(es) on chromatin.
Catalog #L4595-50J
Positive Control HeLa or Jurkat cell extracts
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry (Fr) (paraffin-embedded sections). Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No8L604
HostMouse
SourceHuman
Concentration~1mg/ml
FormAs reported
PurityPurified by Protein A affinity chromatography.
ImmunogenNi-NTA purified truncated recombinant human LSD1 expressed in E. Coli strain BL21 (DE3).
SpecificitySpecies Crossreactivity: Human. Other species have not been tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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