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You are here:Home » Antibodies » Abs to Enzymes, Deacetylase » Anti -LSD1 (Lysine-Specific Histone Demethylase, Amine Oxidase Flavin-containing Domain Protein 2, AOF2, BRAF35-HDAC Complex Protein BHC110, Flavin-containing Amine Oxidase Domain-containing Protein 2, KDM1, KDM1A, KIAA0601, Lysine-specific Histone Demethylase

Anti -LSD1 (Lysine-Specific Histone Demethylase, Amine Oxidase Flavin-containing Domain
Protein 2, AOF2, BRAF35-HDAC Complex Protein BHC110, Flavin-containing Amine Oxidase
Domain-containing Protein 2, KDM1, KDM1A, KIAA0601, Lysine-specific Histone Demethylase

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Lysine-specific histone demethylase (LSD1) is a ubiquitously expressed nuclear protein belonging to the flavin monoamine oxidase family.
Catalog #L4595-50M
Histone modifications mediate changes in gene expression by altering chromatin structure or by serving as a platform to recruit other proteins. LSD1 is an amine oxidase that catalyzes the lysine-specific demethylation of histone proteins via an FAD-dependent oxidative reaction. Methylation on histone H3-K9 is thought to play an important role in heterochromatin formation, while methylation on arginine and some lysine residues, e.g H3-K4, are associated with active transcription.
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1-2ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to an 17 amino acid sequence from near the amino terminus of human Lysine-specific histone demethylase.
SpecificityRecognizes lysine-specific histone demethylase (LSD1). Species Crossreactivity: mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesEC=1.-.-.-, Lysine (K)-specific Demethylase 1A


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