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You are here:Home » Antibodies » Abs to Cell Surface Proteins » Anti -Ly-6C (Lymphocyte Antigen 6 Complex, Locus C)

Anti -Ly-6C (Lymphocyte Antigen 6 Complex, Locus C)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Purified FC
Ly-6C is a member of the Ly-6 multigene family of type V glycophosphatidylinositol-anchored cell surface proteins. It is expressed on bone marrow cells, monocytes/macrophages, neutrophils, endothelial cells, and T-cell subsets. Mice with the Ly-6.2 allotype (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have subsets of CD4+Ly-6C+ and CD8+Ly-6C+ cells, while Ly-6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have only CD8+Ly-6C+ lymphocytes. Ly-6C may play a role in the development and maturation of lymphocytes.1-4
Catalog #L7715-35
ApplicationsSuitable for use in Flow Cytometry and In vitro activation of T-lymphocytes. Other applications not tested.
Recommended DilutionFlow Cytometry: 1ug/10e6 cells
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2c,k
Clone NoHK1.4
HostRat
SourceMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in 100mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added.
PurityPurified
ImmunogenL3 cloned CTL cells
SpecificityRecognizes mouse Ly-6C, Mr 18kD.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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