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You are here:Home » Antibodies » Abs to Cell Surface Proteins » Anti -Ly-6C (Lymphocyte Antigen 6 Complex, Locus C)

Anti -Ly-6C (Lymphocyte Antigen 6 Complex, Locus C)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Supernatant B IP FC
Ly-6C is a member of the Ly-6 multigene family of type V glycophosphatidylinositol-anchored cell surface proteins. It is expressed on bone marrow cells, monocytes/macrophages, neutrophils, endothelial cells, and T-cell subsets. Mice with the Ly-6.2 allotype (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have subsets of CD4+Ly-6C+ and CD8+Ly-6C+ cells, while Ly-6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have only CD8+Ly-6C+ lymphocytes. Ly-6C may play a role in the development and maturation of lymphocytes.
Catalog #L7715-35D
ApplicationsSuitable for use in Flow Cytometry, Western Blot, T-cell activation and Immunoprecipitation. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2c
Clone NoHK1.4
HostRat
SourceMouse
ConcentrationNot determined.
FormSupplied as a liquid.
PurityTissue Culture Supernatant
ImmunogenMurine Ly-6C (T-cell activating).
SpecificityRecognizes extracellular domain of Murine Ly-6C (T-cell activating).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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