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You are here:Home » Antibodies » Antibodies-Nuclear Proteins » Anti -LYAR (Ly1 Antibody Reactive Homolog (Mouse), Cell Growth-regulating Nucleolar Protein, FLJ20425, LYAR, PNAS-5, ZLYAR)

Anti -LYAR (Ly1 Antibody Reactive Homolog (Mouse), Cell Growth-regulating Nucleolar
Protein, FLJ20425, LYAR, PNAS-5, ZLYAR)


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Clone Host Grade Applications
Polyclonal Sheep Affinity Purified B IC
LYAR (Ly-1/CD5 antibody reactive clone) is a 45-50kD nucleolar protein that was named for the ability of its antibody to cross-react with Ly-1. Its function is unclear; it is known to associate with MYCN and RRP1B, the latter association giving rise to the suggestion that LYAR is involved with RNA metabolism. Human LYAR is 379aa in length. It contains two C2H2-type Zn finger regions (aa6-25, 33-51) followed by one coiled-coil region (aa175-219) and an NLS (aa217-222). There are multiple Zn-binding sites and three utilized phosphorylation sites at aa244, aa258 and aa276. Over aa288-379, human LYAR shares 75aa identity with mouse LYAR.
Catalog #L7765-01
ApplicationsSuitable for use in Western Blot and Immunocytochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.1ug/ml
Immunocytochemistry: 5-15ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
ConcentrationNot determined
FormSupplied as a lyophilized powder in PBS, trehalose. Reconstitute with sterile PBS to 200ug/ml.
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant corresponding to aa288-379 from human LYAR expressed in E. coli (Q9NX58).
SpecificityRecognizes human LYAR.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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