You are here:Home
»
Antibodies
»
Abs to Amino Acids
»
Anti -Lysine, acetylated, N Epsilon (Acetyl-Lysine)
Anti -Lysine, acetylated, N Epsilon (Acetyl-Lysine)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Ascites |
E B IH |
|
| Nucleosome composition varies considerably from one chromosomal domain to the next, with a major variable being histone acetylation. The level of histone acetylation also correlates directly with the transcriptional activity of a particular domain. Histone acetylation destabilizes the nucleosome structure and renders the DNA more accessible to transcription factors. This destabilization is the result of the reduction in the capacity of the acetylated N-terminal tails to stabilize the path of DNA in the nucleosome through charge neutralization. Recent studies of the several enzymes involved in acetylation and deacetylation of histone residues have revealed a possible relationship between gene transcriptional activation, histone acetylation and tumor suppressor function. | | | Catalog # | L9058-06 | | Applications | Suitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications have not been tested. | | Recommended Dilution | ELISA: 1:5000-1:50,000 | | Immunohistochemistry: 1:500-1:5000 | | Western Blot: 1:500-1:5000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1,k | | Clone No | 3C155 | | Host | Mouse | | Concentration | Not Determined | | Form | Supplied as a lyophilized powder. No preservatives added. Reconstitute with 200ul sterile ddH2O. | | Purity | Ascites | | Immunogen | Acetyl lysine, N epsilon. | | Specificity | Recognizes Ne-acetyl lysine, N-acetyl putrescine and acetylated histones. There is no crossreactivity with either propionyl lysine or butyryl lysine. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
