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Anti -Lysosome Associated Membrane Protein 3 (LAMP 3, Dendritic Cell Lysosome Associated Membrane Protein, DC-LAMP, CD208) (PE)
Anti -Lysosome Associated Membrane Protein 3 (LAMP 3, Dendritic Cell Lysosome Associated
Membrane Protein, DC-LAMP, CD208) (PE)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Purified |
FC |
|
| DC-LAMP (dendritic cell lysosome-associated membrane protein: also known as CD208 and LAMP3) is a 50-70kD member of the LAMP family of proteins. Mature human DC-LAMP is a 389 amino acid (aa) type I transmembrane protein. It has a 254 aa lumenal N-terminus and a short 14 aa cytoplasmic tail. The molecule is found in type II pneumocytes, interdigitating DC, and various tumors. DC-LAMP serves as a marker of human mature DC, and it may play a role in normal lysosome and endosome function. Over the region used as immunogen, human DC-LAMP shares 72% and 55% aa sequence identity with canine and mouse DC-LAMP, respectively. | | | Catalog # | L9190-20P | | Applications | Suitable for use in Flow Cytometry. Other applications not tested. | | Recommended Dilution | Flow Cytometry: Use 10ul to label 10e6 cells. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in PBS, 0.1% sodium azide. Labeled with PE. | | Purity | Purified | | Immunogen | NS0-derived rhDC-LAMP lumenal domain | | Specificity | Recognizes human DC-LAMP. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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