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Macrophage Colony Stimulating Factor, Recombinant, Human (M-CSF, CSF-1, Lanimostim, Macrophage colony-stimulating factor 1 precursor, MCSF, M-CSF, MGC31930)
Macrophage Colony Stimulating Factor, Recombinant, Human (M-CSF, CSF-1, Lanimostim, Macrophage colony-stimulating factor 1 precursor, MCSF, M-CSF, MGC31930)
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| Macrophage Colony Stimulating Factor (M-CSF) is produced by various cell types, including fibroblasts, macrophages and endothelial cells. This colonly stimulating factor is involved in both the development and function of monocytes/macropahges. Human M-CSF is a disulfide-linked homodimer composed of 18.4kD subunits of 158 amino acid residues. | | | Catalog # | M1201 | | Biological Activity | Human M-CSF is fully biologically active when compared to standards. The ED50 as determined by the dose-dependent stimulation of the proliferation of murine M-NFS-60 cells is 5 ng/ml, corresponding to a specific activity of 2x10e5 units/mg. | | . | | Storage and Stability: | | Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile ddH2O, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Country of Origin | USA | | Molecular Weight | 36.8kD | | Source | E. coli | | Purity | 98% (SDS-PAGE and HPLC analyses). Endotoxin: 0.1ng/ug (1EU/ug). | | Form | Supplied as a lyophilized powder from a sterile filtered solution in PBS, pH 8.0..Reconstitute with sterile, ddH2O to 0.1-0.5 mg/ml. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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