Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Growth Factors, Cytokines » Growth Factors-M-CSF » Macrophage Colony Stimulating Factor, Recombinant, Human (M-CSF, CSF-1, Lanimostim, Macrophage colony-stimulating factor 1 precursor, MCSF, M-CSF, MGC31930)

Macrophage Colony Stimulating Factor, Recombinant, Human (M-CSF, CSF-1, Lanimostim,
Macrophage colony-stimulating factor 1 precursor, MCSF, M-CSF, MGC31930)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Macrophage colony stimulating factor (M-CSF) is one of the glycoproteins called colony-stimulating factors (CSFs).A mononuclear phagocyte colony-stimulating factor (M-CSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. Some clinical investigations have shown autologous production of M-CSF various human cell lines in vitro and by tumors in vivo.
Catalog #M1201A
Recombinant Human M-CSF is a disulfide linked homodimer, non-glycosylated, polypeptide chain containing 2 x 159 amino acids and having a total molecular mass of 36.8kD.
SequenceThe sequence of the first five N-terminal amino acids was determined and was found to be Met-Glu-Glu-Val-Ser.
Biological ActivityM-CSF is fully biologically active when compared to standard. The ED50, calculated by the dose-dependent stimulation of the proliferation of murine M-NFS-60 indicator cells was found <1ng/ml, corresponding to a Specific Activity of 1 x 10e6 IU/mg.
EndotoxinLess than 0.1ng/ug (IEU/ug) of M-CSF.
Storage and StabilityStore powder dessicated at -20ºC. Liquid can be stored at 4ºC for 2-7 days, long term at -20ºC. For long term it is recommended to add a carrier protein (0.1% HSA or BSA). Aliquot to prevent repeated freeze-thaw cycles.
SourceRecombinant, Human (E. coli)
Purity95% by RP-HPLC, FPLC, or reducing/non-reducing SDS-PAGE Silver Stain. Chromatographically purified. Endotoxin: 0.1ng/ug (IEU/ug)
FormSupplied as a lyophilized powder in HSA, Manntiol. Reconstitute sterile ddH2O, 0.1% HSA or BSA to 100ug/ml, which can then be further diluted to other aqueous solutions
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links