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You are here:Home » Growth Factors, Cytokines » Growth Factors-M-CSF » Macrophage Colony Stimulating Factor, Recombinant, Human (M-CSF, CSF-1, Lanimostim, Macrophage colony-stimulating factor 1 precursor, MCSF, M-CSF, MGC31930)

Macrophage Colony Stimulating Factor, Recombinant, Human (M-CSF, CSF-1, Lanimostim,
Macrophage colony-stimulating factor 1 precursor, MCSF, M-CSF, MGC31930)

Pricing

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Specifications

Macrophage colony stimulating factor (M-CSF) is one of the glycoproteins called colony-stimulating factors (CSFs).A mononuclear phagocyte colony-stimulating factor (M-CSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. Some clinical investigations have shown autologous production of M-CSF various human cell lines in vitro and by tumors in vivo.
Catalog #M1201C
Endotoxin<0.1EU/ug
Biological Activity M-CSF is fully biologically active when compared to standard. The ED50, calculated by the dose-dependent stimulation of the proliferation of murine M-NFS-60 indicator cells was found < 5ng/ml, corresponding to a Specific Activity of 2x105 IU/mg.
AA SequenceMEEVSEYCSH MIGSGHLQSL QRLIDSQMET SCQITFEFVD QEQLKDPVCY LKKAFLLVQD IMEDTMRFRD NTPNAIAIVQ LQELSLRLKS CFTKDYEEHD KACVRTFYET PLQLLEKVKN VFNETKNLLD KDWNIFSKNC NNSFAECSSQ GHERQSEGS
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O, aliquot and store at -20°C. For long term it is recommended to add a carrier protein (0.1% HSA or BSA). For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight36.8kD
SourceRecombinant, human, E. coli
Purity~95% Analysis by RP-HPLC; Reducing and non-reducing SDS-PAGE.
FormSupplied as a lyophilized powder from 5mM sodium phosphate, pH 8, and 100mM sodium chloride.
ReconstitutionReconstitute with sterile ddH2O to 0.1mg/ml which can be further diluted into other aqueous solutions. It is recommended to add a carried protein (0.1% HSA or BSA) for long term storage.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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