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You are here:Home » Molecular Biology » Growth Factors-MIP » Macrophage Inflammatory Protein 2-alpha, Recombinant, Human (CXCL2, Chemokine (C-X-C Motif) Ligand 2, CINC-2a, GRO2, GROb, GROB, Gro-beta, Growth-regulated Protein beta, Macrophage Inflammatory Protein 2-alpha Precursor, MGSA-b, MGSA beta, MIP2, MIP2A, MI

Macrophage Inflammatory Protein 2-alpha, Recombinant, Human (CXCL2, Chemokine (C-X-C
Motif) Ligand 2, CINC-2a, GRO2, GROb, GROB, Gro-beta, Growth-regulated Protein beta,
Macrophage Inflammatory Protein 2-alpha Precursor, MGSA-b, MGSA beta, MIP2, MIP2A, MI

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Specifications

Chemokine (C-X-C motif) ligand 2 (CXCL2) is a small cytokine belonging to the CXC chemokine family that is also called macrophage inflammatory protein 2-alpha (MIP2-alpha), Growth-regulated protein beta (Gro-beta) and Gro oncogene-2 (Gro-2). CXCL2 is 90% identical in amino acid sequence as a related chemokine, CXCL1. This chemokine is secreted by monocytes and macrophages and is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells. The gene for CXCL2 is located on human chromosome 4 in a cluster of other CXC chemokines.[CXCL2 mobilizes cells by interacting with a cell surface chemokine receptor called CXCR2.
Catalog #M1202-53A
SourceYeast
Biological ActivityThe biological activity of recombinant human MIP-2&# alpha is determined by its use as a cofactor for CSF-dependent myelopoiesis.
Storage and StabilityLyophilized powder may be stored at -20°C. Reconstitute to with sterile dH2O or buffer, aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceYeast
PurityPurified. 95% pure by SDS gel electrophoresis.
ConcentrationAs reported
FormSupplied as a lyophilized powder in PBS, 20mM HEPES/0.1M NaCl ph7.3
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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